A Different Clinical Type of OSAS: REM-Related OSASHandan Inönü Köseoğlu1, Asiye Kanbay2, Osman Demir31Department of Chest Diseases, Gaziosmanpaşa University Faculty of Medicine, Tokat 2Department of Chest Diseases, Medeniyet University Faculty of Medicine, İstanbul 3Department of Biostatistics and Medical Informatics, Gaziosmanpaşa University Faculty of Medicine, Tokat
Objective: Rapid Eye Movement (REM) is an entity in which collapsibility of upper respiratory tract increases. Different opinions have been proposed definition of REM-related obstructive sleep apnea syndrome (OSAS). Some authors classify REM-related OSAS as the first presentation or others as a different clinical type of OSAS. We aimed to compare clinical and polysomnographic findings of REM-related and non REM-related OSAS patients to test whether REM-related OSAS is a different clinical type OSAS or manifestation of early stage or onset of OSAS. Methods: The study had a retrospective design. Patients with initial diagnosis of sleep related breathing disorders, were later diagnosed as OSAS based on apnea-hypopnea index (AHI) ≥ 5, and divided into two groups: Patients with AHINREM < 5 and, AHIREM / AHINREM >2 whose REM recordings were obtained for at least 30 minutes were defined as “REM-related OSAS”, and those who refute this description as “non REM-related OSAS.” Results: A total of 329 cases with a mean age of 51 ± 10 years were included in the study. Thirty-five (10.6 %) cases of OSAS were REM-related, 294 (89.4 %) of them were non REM-related. Age, body mass index, smoking status, and concomitant diseases were comparable between groups (p>0.05). In REM related cases AHI were lower, duration of REM was longer, and mean oxygen saturations were comparatively higher (p<0.05). Conclusion: Similarities between groups as for age, body mass index, concomitant disease suggest that REM-related OSAS is a different clinical type of OSAS, rather than early phase of OSAS. Keywords: Obstructive sleep apnea syndrome, REM dependency, REM-related obstructive sleep apnea syndrome
Handan Inönü Köseoğlu, Asiye Kanbay, Osman Demir. A Different Clinical Type of OSAS: REM-Related OSAS. Eurasian J Pulmonol. 2015; 17(2): 92-97
Corresponding Author: Handan Inönü Köseoğlu, Türkiye |
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