The relationship between obesity and demographic characteristics, severity of disease and atopy in asthma patients

Talay, Fahrettin; Kurt, Bahar

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The relationship between obesity and demographic characteristics, severity of disease and atopy in asthma patients [Eurasian J Pulmonol]

Eurasian J Pulmonol. 2008; 10(3): 163-167

The relationship between obesity and demographic characteristics, severity of disease and atopy in asthma patients

Fahrettin Talay, Bahar Kurt
Abant Izzet Baysal University School Of Medicine, Department Of Chest Diseases, Bolu, Turkey

AIM: In this study we aimed to evaluate the relationship between obesity and gender, age, education status, atopy and severity of disease in asthma patients.
MATERIALS-METHOD: Asthmatics diagnosed in our chest diseases clinic (261 patients) were enrolled to study, and their BMI (kg/m2) were analyzed.
RESULTS: The mean age of asthmatic patients (195 female, 66 male) was 48.4 � 16.2. Frequency of obesity in female asthmatics was higher than in male asthmatics (in females 44%, in males 23%; p<0.05). In female asthmatics older than 50 years, and in those education level was primary school or lower, frequency of obesity was higher (p<0.001). There was no relationship between obesity and atopy (p>0.05). Severity of disease was found to be correlated with the increase in the frequency of obesity (p<0.001). Also in all patients there was linear relationship in spearman correlation between BMI and asthma severity (r = 0.326, p<0.001) and age (r = 0.361, p<0.001). A negative correlation between BMI and FVC value (r = -0.325, p<0.001) was detected. In the multivariate logistic regression analysis, risk factors for obesity were found to be as follows: Female asthmatics older than 50 years [odds ratio (OR) = 2.2, 95% confidence interval (CI) = 1.2�4.0], education level of primary school or lower (OR = 2.8, 95% CI) = 1.4�5.5, moderate persistent asthma (OR = 5.1, 95% CI = 1.3�19.4), and severe persistent asthma (OR = 5.1, 95% CI = 1.3�21.6).
CONCLUSION: In this study, frequency of obesity in female asthmatics was higher in lower educational level and in age older than 50 years. Severity of disease correlated with frequency of obesity. The causative relation between obesity and severity of asthma needs to be clarified with new and more detailed studies.

Keywords: asthma, obesity, severity of disease, atopy

Ast�ml� hastalarda obezite ile demografik �zellikler, hastal�k �iddeti ve atopi aras�ndaki ili�ki

Fahrettin Talay, Bahar Kurt
Abant �zzet Baysal �niversitesi, �zzet Baysal T�p Fak�ltesi, G��s Hastal�klar� Ana Bilim Dal�, Bolu

AMA�: Bu �al��mada ast�ml� hastalarda obezite ile cinsiyet, ya�, e�itim durumu, atopi ve hastal�k �iddeti aras�ndaki ili�kiyi incelemeyi ama�lad�k.
GERE�-Y�NTEM: G��s Hastal�klar� poliklini�imizde ast�m tan�s� konulan 261 hasta �al��maya al�nd�. Hastalar�n v�cut kitle indeksi (VK�) (kg/m2) hesapland�.
BULGULAR: Bu �al��madaki ast�ml�lar�n (195 kad�n, 66 erkek) ya� ortalamas� 48.4 � 16.2 idi. Kad�n hastalarda erkek hastalara g�re obezite s�kl�� daha fazla idi (Kad�nlarda %44, erkeklerde %23, p= 0.003). Elli ya��n �zerinde ve ilkokul ve daha d��k e�itimli kad�n ast�ml�larda obezite s�kl�� daha fazla idi (p<0.001). Ast�ml�larda obezite ile atopi aras�nda bir ili�ki bulunmad� (p>0.05). Hastal�k �iddeti artt�k�a obezite s�kl��n�n artt�� saptand� (p<0.001). Ast�ml� hastalarda spearman korelasyon katsay�s�nda VK� ile ast�m �iddeti (r = 0.326, p<0.001) ve ya� (r = 0.361, p<0.001) aras�nda do�rusal ili�ki saptand�. VK� ile FVC de�eri aras�nda ise negatif ili�ki (r = -0.325, p<0.001) saptand�. Multivariate lojistik regresyon analizinde obezite i�in risk fakt�rleri �u �ekilde bulundu. Elli ya��n �zerinde [odds ratio (OR) = 2.2, 95% confidence interval (CI) = 1.2�4.0], ilkokul ve daha d��k seviyede e�itimli (OR = 2.8, 95% CI = 1.4�5.5), orta persistan ast�ml� (OR = 5.1, 95% CI = 1.3�19.4) ve ileri persistan ast�ml� olmak (OR = 5.1, 95% CI = 1.3�21.6).
SONU�: Bu �al��mada �zellikle d��k e�itimli ve 50 ya� �zerindeki kad�n ast�ml�larda obezite s�kl�� daha fazla saptand�. Ast�m �iddeti artt�k�a obezite s�kl�� da artmaktayd�. Ast�m �iddeti ile obezite aras�ndaki nedensel ili�kinin a��klanabilmesi i�in daha detayl� �al��malar yararl� olacakt�r.

Anahtar Kelimeler: ast�m, obezite, hastal�k �iddeti, atopi

Fahrettin Talay, Bahar Kurt. The relationship between obesity and demographic characteristics, severity of disease and atopy in asthma patients. Eurasian J Pulmonol. 2008; 10(3): 163-167

Corresponding Author: Fahrettin Talay, T�rkiye

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